タイトル

開講年度 開講学部等
2025 理学部
開講学期 曜日時限 授業形態 AL(アクティブ・ラーニング)ポイント
後期 月3~4 講義 3.0
時間割番号 科目名[英文名] 使用言語 単位数
1042400015 定量生物学[Quantitative Biology] 日本語 2
担当教員(責任)[ローマ字表記] メディア授業
原 裕貴[HARA Yuki]
担当教員[ローマ字表記]
原 裕貴 [HARA Yuki]
特定科目区分   対象学生 生物学科学生対象 対象年次 2~4
ディプロマ・ポリシーに関わる項目 カリキュラムマップ(授業科目とDPとの対応関係はこちらから閲覧できます)
授業の目的と概要
It has been increasing opportunities for understanding quantitatively biological topics. This lecture focuses mainly on cellular phenomena and introduces the methods and significance of quantification by explaining research examples.
授業の到達目標
To foster an ability to consider biological topics at the cellular level from the viewpoints of 'number', 'quantity', 'form', and 'force'.
授業計画
【全体】
Explaining the topics in the field of 'quantitative biology'. Based on this, think and debate how to quantify and what the significance of quantification is.
項目 内容 授業時間外学習 備考
第1回 What is the quantitative biology? Thinking about a definition of "quantification" reviewing (240 min)
第2回 Size and number of the cellular components Thinking about what the components of the cell are preparation (120 min), reviewing (120 min)
第3回 Size scaling in biology Thinking about size rule and variety preparation (120 min), reviewing (120 min)
第4回 Size scaling in the cell Thinking about the size rule and variety in the cell preparation (120 min), reviewing (120 min)
第5回 Proliferation and cell cycle in quantitative biology Thinking about Proliferation and cell cycle preparation (120 min), reviewing (120 min)
第6回 Molecular motors and cytoskeleton in quantitative biology Thinking about molecular motors and cytoskeletons, and their functions preparation (120 min), reviewing (120 min)
第7回 Cell division in quantitative biology (1) Thinking about the apparatus of chromosome segregation preparation (120 min), reviewing (120 min)
第8回 Cell division in quantitative biology (2) Thinking about the apparatus of cell division and cytokinesis preparation (120 min), reviewing (120 min)
第9回 Organelle structure in quantitative biology Thinking about Organelle structure and its function preparation (120 min), reviewing (120 min)
第10回 Size and morphology in organelles (1) Thinking about organelle size preparation (120 min), reviewing (120 min)
第11回 Applied forces to organelle positioning Thinking about organelle positioning inside the cell preparation (120 min), reviewing (120 min)
第12回 Size and morphology in organelles (2) Thinking about organelle Size and morphology in organelles preparation (120 min), reviewing (120 min)
第13回 Dynamics of molecules in quantitative biology Thinking about the behavior and dynamics of intracellular models preparation (120 min), reviewing (120 min)
第14回 Chromatin structure in quantitative biology Thinking about the chromatin structure inside the nucleus and its functional viewpoint preparation (120 min), reviewing (120 min)
第15回 synthetic biology & Unsolved problems Thinking about the chromatin structure for organizing the condensed chromosomes and introducing synthetic biology methods preparation (120 min), reviewing (120 min)
第16回 Summary Discussing the unsolved problems in this field and summarizing the previous lectures reviewing (240 min)
※AL(アクティブ・ラーニング)欄に関する注
・授業全体で、AL(アクティブ・ラーニング)が占める時間の割合を、それぞれの項目ごとに示しています。
・A〜Dのアルファベットは、以下の学修形態を指しています。
【A:グループワーク】、【B:ディスカッション・ディベート】、【C:フィールドワーク(実験・実習、演習を含む)】、【D:プレゼンテーション】
A: 10% B: 10% C: --% D: 10%
成績評価法
Evaluating the attitude for debate (10% for evaluation) and the report in each lecture (90% for evaluation).
教科書にかかわる情報
備考
participants will get resumes in every lecture.
参考書にかかわる情報
参考書 書名 細胞建築学入門 ISBN 9784777520954
著者名 木村暁著 出版社 工学社 出版年 2019
参考書 書名 定量生物学 : 生命現象を定量的に理解するために ISBN 9784759817300
著者名 小林徹也編 出版社 化学同人 出版年 2018
参考書 書名 Cell biology by the numbers ISBN 9780815345374
著者名 Ron Milo, Rob Phillips ; illustrated by Nigel Orme 出版社 Garland Science 出版年 2016
参考書 書名 Physical biology of the cell ISBN 9780815344506
著者名 Rob Phillips ... [et al.] ; illustrated by Nigel Orme 出版社 Garland Science 出版年 2013
備考
メッセージ
We will use the Slack app to communicate with each other and to submit reports in this lecture.
We will also give the recording video of the lecture and prepare the online lecture to respond to some difficult situations, including COVID-19.
We don't mind the faculty and department where you belong and the language. In this lecture, we will officially use the Japanese language. But, if you want, we will help you to understand the topics of this lecture in English after the scheduled lecture time.
キーワード
cell, organelle, cytoskeleton, biophysics, mathematics, scaling
持続可能な開発目標(SDGs)

関連科目
Cell Biology, Biophysics, Developmental Cell Biology, Molecular Biology
履修条件
連絡先
Yuki
yukihara@yamaguchi-u.ac.jp
オフィスアワー
Anytime you want. Especially, I will set the time from 16:00 to 17:30 every Monday, which is only for helping you to understand and taking any questions from you.

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