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メディア授業とは，メディアを利用して遠隔方式により実施する授業の授業時数が，総授業時数の半数を超える授業をいいます。
メディア授業により取得した単位は，卒業要件として修得すべき単位のうち60単位を超えないものとされています。
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The knowledge of synthetic organic chemistry is indispensable for synthesizing organic compounds such as pharmaceuticals and functional materials. In the lecture, the important and latest synthetic methodologies will be presented. You are required to improve your synthetic knowledge through problem sets. By taking this class, you can obtain fundamental knowledge as a specialist in synthetic organic chemistry.
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To be able to understand the basic methodologies used in modern synthetic organic chemistry.
To be able to draw a reasonable reaction mechanism for each transformations.
To be able to propose a reasonable synthetic route for target molecules.
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The main topic of this class is important and latest methodologies for chemical synthesis of organic molecules at the graduate school level. The lectures will be given along with the textbook with a projector. Quiz will be given at the beginning of the every lectures to encourage your study at home. Attendance will be checked by submission of the quiz answer sheet.
As far as the number of students is within the capacity of the lecture room specified by the guidelines of Yamaguchi University, face-to-face classes will be held. Online classes may be held depending on the situation. The change will be announced by Shugaku-shien system (e-mail).
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第1回
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Chap. 1 Synthetic Design
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retrosynthetic analysis
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第2回
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Chap. 1 Synthetic Design
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synthetic plan
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第3回
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Chap. 2 Stereochemical Consideration in Planning Synthesis
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conformational analysis
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第4回
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Chap. 2 Stereochemical Consideration in Planning Synthesis
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conformation and reactivity
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第5回
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Chap. 3 The Concept of Protecting Functional Groups
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protecting groups
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第6回
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Chap. 4 Functional Group Transformations
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oxidations
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第7回
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Chap. 4 Functional Group Transformations
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reductions
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第8回
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Chap. 4 Functional Group Transformations
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stereoselective reactions
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第9回
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Chap. 5 Functional Group Transformations
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carbon-carbon pai-bonds
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第10回
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Chap. 6 Formation of Carbon-Carbon Single bonds via Enolate Anions
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alkylation
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第11回
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Chap. 6 Formation of Carbon-Carbon Single bonds via Enolate Anions
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aldol reaction
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第12回
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Chap. 7 Formation of Carbon-Carbon Single bonds via Organometallic Reagents
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organometallic reagents
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第13回
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Chap. 8 Palladium-Catalyzed Coupling Reactions
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palldaium-catalyzed reactions
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第14回
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Chap. 9 Formation of Carbon-Carbon pai-bonds
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double bonds and triple bonds
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第15回
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Chap. 10 Synthesis of Carbocyclic Systems
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Carbocycles
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※AL（アクティブ・ラーニング）欄に関する注
・授業全体で、AL（アクティブ・ラーニング）が占める時間の割合を、それぞれの項目ごとに示しています。
・A〜Dのアルファベットは、以下の学修形態を指しています。
【A：グループワーク】、【B：ディスカッション・ディベート】、【C：フィールドワーク（実験・実習、演習を含む）】、【D：プレゼンテーション】
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A: --% B: --% C: 5% D: --%
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Grading is based on the quizzes (100%).
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最新有機合成法 設計と戦略 (第２版)
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9784759819618
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G.S.Zweifel (著), M.H.Nantz (著), P. Somfai (著), 檜山 爲次郎 (翻訳)
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化学同人
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2018
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備考
"Modern Organic Synthesis" and "演習で学ぶ有機反応機構" are selected as a textbook in order to give the lecture along with them, but purchase is not mandatory.
A projector will be used in the lecture. Most of the lecture materials and the quiz are came from the textbook.
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ウォーレン有機化学 上・下（第2版）
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9784807908714
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Jonathan Clayden (著), Stuart Warren (著), Nick Greeves (著), 野依 良
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東京化学同人
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2015
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備考
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Please find any textbooks that suits yourself to study, since many books relating to organic chemistry are collected in the library.
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This class is for students majoring in synthetic organic chemistry. The lecture will be the most appropriate for students who have already mastered the basic organic chemistry courses and who want to study more advanced synthetic organic chemistry at the graduate school level.
Students, who do not aim to obtain credits, are also welcome to attend the class.
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Synthetic organic chemistry
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| (教育)すべての人に包摂的かつ公正な質の高い教育を確保し、生涯学習の機会を促進する。 |
| (エネルギー)すべての人々の、安価かつ信頼できる持続可能な近代的エネルギーへのアクセスを確保する。 |
| (持続可能な生産と消費)持続可能な生産消費形態を確保する。 |
| (気候変動)気候変動及びその影響を軽減するための緊急対策を講じる。 |
| (海洋資源)持続可能な開発のために海洋・海洋資源を保全し、持続可能な形で利用する。 |
| (陸上資源)陸域生態系の保護、回復、持続可能な利用の推進、持続可能な森林の経営、砂漠化への対処、ならびに土地の劣化の阻止・回復及び生物多様性の損失を阻止する。 |
| (実施手段)持続可能な開発のための実施手段を強化し、グローバル・パートナーシップを活性化する。 |
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Bioorganometallic Chemistry, Advanced Organic Metal Reaction Chemistry, Advanced Organic Reaction Chemistry
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Students, who do not aim to obtain credits, are also welcome to attend the class.
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Please ask me after class when you have a question.
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