タイトル

開講年度 開講学部等
2025 大学院創成科学研究科（博士前期）
開講学期 曜日時限 授業形態 AL（アクティブ・ラーニング）ポイント
前期集中 集中   10.0
時間割番号 科目名[英文名] 使用言語 単位数
3272170007 生物機能科学特別講義Ⅲ[Special lecture for Biological Sciences Ⅲ] 日本語 1
担当教員（責任）[ローマ字表記] メディア授業
非常勤 講師 ー
担当教員[ローマ字表記]
非常勤 講師, 井内　良仁　[IUCHI Yoshihito]
特定科目区分   対象学生   対象年次 1～2
ディプロマ・ポリシーに関わる項目 カリキュラムマップ(授業科目とDPとの対応関係はこちらから閲覧できます)
授業の目的と概要
This course focuses on drug discovery. Atsushi Manabe, President and CEO of Daiichi Sankyo, Kenji Yasukawa, President and CEO of Astellas Pharma, and Asuka Miyabayashi, a Japanese executive at Takeda Pharmaceutical, all graduated from faculties of agriculture. In the pharmaceutical industry, there are numerous employees with agricultural backgrounds earning over 100 million yen annually, making pharmaceutical companies strong candidates for your future career.

You will learn about the current state of drug discovery and modern pharmaceutical technologies, with the goal of contributing to the development of new drugs that can save future generations.

The instructor is a practicing physician involved in drug discovery, serving as an advisor to pharmaceutical companies. With hands-on experience in preclinical and clinical trials, the instructor will provide a highly practical and realistic learning experience.
授業の到達目標
1. Research and gain knowledge about anything that interests you about the lecture content.
2. Don't be passive, but think about what opinions you would express (write) if you were in a situation like that.
3. Be able to understand somewhat difficult content by researching it yourself and asking questions.
4. Be able to think independently and proactively.
5. Be able to think deeply about content that differs from your previous opinions and ways of thinking.
授業計画
【全体】
You will first gain a broad understanding of the overall industrial structure of the pharmaceutical industry, then break down and study each step of the drug discovery process in detail.

Please bring an internet-connected laptop or smartphone for research purposes, along with writing materials and a notebook.
項目 内容 授業時間外学習 備考
第1回 Introduction to the Global Pharmaceutical Industry Students will be informed about the course objectives, grading criteria, and lecture format. Additionally, they will learn about the structure of the pharmaceutical industry from a global perspective. Students are expected to review the distributed lecture materials and reference books, spending 2 hours on preparatory study and 2 hours on review.
第2回 The Pharmaceutical Industry in Japan Students will learn about the pharmaceutical industry in Japan. Students are expected to review the distributed lecture materials and reference books, spending 2 hours on preparatory study and 2 hours on review.
第3回 Pipeline Students will learn about the overall process of drug discovery using multiple modalities, including small molecules, antibodies, nucleic acids, and peptides. Students are expected to review the distributed lecture materials and reference books, spending 2 hours on preparatory study and 2 hours on review.
第4回 Seed Discovery Students will learn about the initial step of drug discovery. The course will also cover topics such as high-throughput screening (HTS), academia-driven drug discovery, and pharmaceutical ventures. Students are expected to review the distributed lecture materials and reference books, spending 2 hours on preparatory study and 2 hours on review.
第5回 Lead Compounds Students will learn about synthetic development, drug efficacy, and pharmacological testing. Students are expected to review the distributed lecture materials and reference books, spending 2 hours on preparatory study and 2 hours on review.
第6回 Preclinical Trials Students will learn about preclinical trials, including ADME (Absorption, Distribution, Metabolism, and Excretion), safety assessments, and other related evaluations. The course will also cover the IND (Investigational New Drug) application process. Students are expected to review the distributed lecture materials and reference books, spending 2 hours on preparatory study and 2 hours on review.
第7回 Clinical Trials and Follow-Up Students will learn about clinical trials and follow-up processes. Students are expected to review the distributed lecture materials and reference books, spending 2 hours on preparatory study and 2 hours on review.
第8回 Drug Discovery in the Near Future Students will learn about emerging modalities such as regenerative medicine, cell therapy, and digital pharmaceuticals, as well as new technologies like AI-driven drug discovery. Students are expected to review the distributed lecture materials and reference books, spending 2 hours on preparatory study and 2 hours on review.
※AL（アクティブ・ラーニング）欄に関する注
・授業全体で、AL（アクティブ・ラーニング）が占める時間の割合を、それぞれの項目ごとに示しています。
・A〜Dのアルファベットは、以下の学修形態を指しています。
【A：グループワーク】、【B：ディスカッション・ディベート】、【C：フィールドワーク（実験・実習、演習を含む）】、【D：プレゼンテーション】
A: --%　B: 100%　C: --%　D: --%
成績評価法
Students will be required to create and submit a report during each class session, with access to online search tools.
Grading will be based entirely on these reports (100%).
You are allowed to use AI tools such as ChatGPT and Perplexity. In fact, the course is designed with the assumption that everyone will use them, so not utilizing AI may put you at a significant disadvantage.
教科書にかかわる情報
備考
参考書にかかわる情報
備考
メッセージ
キーワード
持続可能な開発目標（SDGs）

  • 貧困をなくそう
  • すべての人に健康と福祉を
  • 質の高い教育をみんなに
  • ジェンダー平等を実現しよう
  • 働きがいも経済成長も
  • 人や国の不平等をなくそう
(貧困)あらゆる場所のあらゆる形態の貧困を終わらせる。
(保健)あらゆる年齢のすべての人々の健康的な生活を確保し、福祉を促進する。
(教育)すべての人に包摂的かつ公正な質の高い教育を確保し、生涯学習の機会を促進する。
(ジェンダー)ジェンダー平等を達成し、すべての女性及び女児の能力強化を行う。
(経済成長と雇用)包摂的かつ持続可能な経済成長及びすべての人々の完全かつ生産的な雇用と働きがいのある人間らしい雇用（ディーセント・ワーク）を促進する。
(不平等)各国内及び各国間の不平等を是正する。
関連科目
履修条件
連絡先
Instructor: Yoshihito Iuchi
083-933-5853
yiuchi@yamaguchi-u.ac.jp
オフィスアワー
As needed

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