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メディア授業とは，メディアを利用して遠隔方式により実施する授業の授業時数が，総授業時数の半数を超える授業をいいます。
メディア授業により取得した単位は，卒業要件として修得すべき単位のうち60単位を超えないものとされています。
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Characteristics of environmentally-benign processes using advanced biocatalysts will be described focusing on the following points.
1. Role of biocatalysts in biological system
2. Liposomal biocatalysts
3. Immobilized biocatalysts
4. Bioreactor design suitable for advanced biocatalysts
5. Current progress in the biocatalysts design and utilization
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General Instructional Objectives are to understand the following points.
1. Role of biocatalysts and immobilized biocatalysts in bioconversion processes
2. Formation, prepration and characteristics of liposomes
3. Functionalization of biocatalysts by using liposomal system
4. Bioreactor design and operation
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The characteristics and applications of phospholipids-based nano-structures for enzyme reactions will be described in the 1st-6th lectures. Then, the preparation and characterization of immobilized biocatalysts and their applications to the practical multiphase reactors will be described.
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第1回
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Structure and function of biocatalysts
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Structure and functions of biocatalysts for bioreactors
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第2回
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Formation of lipid assemblies
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preparation of lipid vesicles (liposomes)
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第3回
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Preparation of lipid assemblies
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Various preparation methods of liposomes
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第4回
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Preparation and characteristics of liposomal enzymes
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Reactivity and stability of enzymes encapsulated in liposomes
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第5回
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Function of liposomal enzymes (1)
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Difference between liposomal and free enzymes
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第6回
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Function of liposomal enzymes (2)
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Applications of enzyme-containing liposomes
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第7回
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Immobilization of biocatalysts
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Immobilization methods of liposomes containing enzymes
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第8回
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Function of immobilized biocatalysts
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Performance of immobilized enzymes
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第9回
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Kinetics of immobilized biocatalyst reactions (1)
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Mass transfer and reaction kinetics of enzymatic reactions in liposomes
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第10回
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Kinetics of immobilized biocatalyst reactions (2)
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Effects of permeability resistance of lipid membranes on the enzymatic reactions in liposomes
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第11回
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Multiphase bioreactors using biocatalysts
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Hydrodynamic and mass transfer properties in gas-liquid-solid three-phase reactors
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第12回
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Operation of multiphase bioreactors
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Characteristics of bioreactors
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第13回
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Current progress in bioreactor design and utilization (1)
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Oxidation reactions
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第14回
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Current progress in bioreactor design and utilization (2)
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Oxidation reactions
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第15回
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Current progress in bioreactor design and utilization (3)
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Energy-saving bioreactors
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※AL（アクティブ・ラーニング）欄に関する注
・授業全体で、AL（アクティブ・ラーニング）が占める時間の割合を、それぞれの項目ごとに示しています。
・A〜Dのアルファベットは、以下の学修形態を指しています。
【A：グループワーク】、【B：ディスカッション・ディベート】、【C：フィールドワーク（実験・実習、演習を含む）】、【D：プレゼンテーション】
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A: --% B: --% C: --% D: --%
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Short Tests and Reports Given in Class 50%, Homework and Assignments 30%, Presentations 20%
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Modified enzyme, Liposomal biocatalyst, Bioreactor design
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| (エネルギー)すべての人々の、安価かつ信頼できる持続可能な近代的エネルギーへのアクセスを確保する。 |
| (持続可能な生産と消費)持続可能な生産消費形態を確保する。 |
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yosimoto@yamaguchi-u.ac.jp
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