|
|
|
|
|
|
メディア授業とは，メディアを利用して遠隔方式により実施する授業の授業時数が，総授業時数の半数を超える授業をいいます。
メディア授業により取得した単位は，卒業要件として修得すべき単位のうち60単位を超えないものとされています。
|
|
|
|
|
|
|
This course outlines the fundamentals of tumor immunology and tumor metabolism (including glycolysis, lactate metabolism, hypoxic response, lipid metabolism, amino acid metabolism, and iron metabolism) to deepen the understanding of how immune cell function is regulated within the tumor microenvironment (TME/TIME). Furthermore, it provides an overview of how metabolism influences therapeutic response, resistance, and adverse events in clinical applications—such as immune checkpoint inhibition, cytokine therapy, cancer vaccines, and cell therapy—thereby bridging these concepts to veterinary clinical research and practice.
|
|
|
|
|
|
|
|
|
|
Acquire a comprehensive understanding of tumor immunology and immunometabolism.
Develop the ability to analyze tumors through the lens of immunology.
Maintain an interest in tumor immunometabolism, grounded in a clinical perspective.
|
|
|
|
|
Systematically study tumor immunology and immunometabolism using resources such as *Yodosha’s Immunology Pedia*, *Yodosha’s Cancer Immunology Pedia*, *Igaku-Shoin’s Standard Immunology*, and the latest research papers. For each session, read the assigned papers (reviews or original research articles) or the relevant pages of the designated reference books, and submit a report summarizing the key points (background, hypothesis, methods, results, limitations, future prospects, etc.) on an A4-sized sheet.
|
|
|
|
|
|
第1回
|
Overview
|
Learn about the content shown on the left.
|
|
第2回
|
Metabolic Reprogramming
|
Learn about the content shown on the left.
|
|
第3回
|
T cell metabolism and function
|
Learn about the content shown on the left.
|
|
第4回
|
Metabolism of tumor-associated macrophages/myeloid cells
|
Learn about the content shown on the left.
|
|
第5回
|
Lactate metabolism and immune suppression
|
Learn about the content shown on the left.
|
|
第6回
|
Hypoxia adaptation and immunity
|
Learn about the content shown on the left.
|
|
第7回
|
Lipid metabolism and immunity
|
Learn about the content shown on the left.
|
|
第8回
|
Amino acid metabolism
|
Learn about the content shown on the left.
|
|
第9回
|
Iron metabolism, redox, and cell death
|
Learn about the content shown on the left.
|
|
第10回
|
Immune checkpoint and metabolism
|
Learn about the content shown on the left.
|
|
第11回
|
Cytokine therapy and metabolism
|
Learn about the content shown on the left.
|
|
第12回
|
Radiation, chemotherapy and metabolism
|
Learn about the content shown on the left.
|
|
第13回
|
Case Studies in Veterinary Oncology: Immunometabolism in Canine and Feline Tumors
|
Learn about the content shown on the left.
|
|
第14回
|
Biomarker and Translational research
|
Learn about the content shown on the left.
|
|
第15回
|
Overview: How to Formulate a Research Hypothesis
|
Learn about the content shown on the left.
|
|
※AL（アクティブ・ラーニング）欄に関する注
・授業全体で、AL（アクティブ・ラーニング）が占める時間の割合を、それぞれの項目ごとに示しています。
・A〜Dのアルファベットは、以下の学修形態を指しています。
【A：グループワーク】、【B：ディスカッション・ディベート】、【C：フィールドワーク（実験・実習、演習を含む）】、【D：プレゼンテーション】
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Please be sure to contact the instructor in charge before registering for the course.
|
|
|
|
|
|
| (教育)すべての人に包摂的かつ公正な質の高い教育を確保し、生涯学習の機会を促進する。 |
|
|
|
|
|
|
|
m.igase@yamaguchi-u.ac.jp
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|